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Citation: Zhou et al., Nature Commun. 2019 10(1):1523.

7 technologies, 29 tissues and cell lines, 22 studies, 390 COVID gene lists.

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Interactome for CoV-1/CoV-2 NSP2 and NSP4.

 IsOMICS Interactome (AP-MS),  SampleType in vitro,  CellType HEK293T,  VirusStrain SARS-CoV-2 isolate Wuhan-Hu-1,  Timepoints 40h,  Perturbations ,  HasCompleteData ,  GeneListSource .

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined100       94 (94%)
COVID079 Interactome_Davis_HEK-293T_40h_NSP2 19 Interactome HEK-293T NSP2 40h 4 (21%) 16 (84%)
COVID080 Interactome_Davis_HEK-293T_40h_NSP4 85 Interactome HEK-293T NSP4 40h 4 (5%) 82 (96%)

scRNA-seq comparison of PBMCs in severe, moderate, convalescent, and healthy donors.

 IsOMICS scRNA-seq, Single-cell T cell receptor (TCR) and B cell receptor (BCR) sequencing,  SampleType patient and healthy samples,  CellType ,  VirusStrain ,  Timepoints n/a,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined418       387 (93%)
COVID351 RNA_Zhang_Monocytes_severe-only_Up 47 scRNA-seq Monocytes Severe SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe patients (n=4) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 14 (30%) 45 (96%)
COVID352 RNA_Zhang_Monocytes_moderate-only_Up 26 scRNA-seq Monocytes Moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 15 (58%) 22 (85%)
COVID353 RNA_Zhang_Monocytes_severe-and-moderate_Up 127 scRNA-seq Monocytes Severe and moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe (n=4) and moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value in severe patients. 87 (69%) 121 (95%)
COVID354 RNA_Zhang_NK-cells_severe-only_Up 45 scRNA-seq NK cells Severe SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe patients (n=4) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 40 (89%) 41 (91%)
COVID355 RNA_Zhang_NK-cells_moderate-only_Up 10 scRNA-seq NK cells Moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 10 (100%) 8 (80%)
COVID356 RNA_Zhang_NK-cells_severe-and-moderate_Up 95 scRNA-seq NK cells Severe and moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe (n=4) and moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value in severe patients. 95 (100%) 87 (92%)
COVID357 RNA_Zhang_T-cells_severe-only_Up 79 scRNA-seq T cells Severe SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe patients (n=4) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 41 (52%) 70 (89%)
COVID358 RNA_Zhang_T-cells_moderate-only_Up 18 scRNA-seq T cells Moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 10 (56%) 14 (78%)
COVID359 RNA_Zhang_T-cells_severe-and-moderate_Up 139 scRNA-seq T cells Severe and moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe (n=4) and moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value in severe patients. 113 (81%) 132 (95%)
COVID360 RNA_Zhang_B-cells_severe-only_Up 81 scRNA-seq B cells Severe SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe patients (n=4) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 21 (26%) 78 (96%)
COVID361 RNA_Zhang_B-cells_moderate-only_Up 28 scRNA-seq B cells Moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value. 17 (61%) 27 (96%)
COVID362 RNA_Zhang_B-cells_severe-and-moderate_Up 74 scRNA-seq B cells Severe and moderate SARS-CoV-2 Healthy donors Post admission SARS-CoV-2 severe (n=4) and moderate patients (n=7) vs. healthy donors (n=5). Singificance defined by p-value < 0.01 and Log2FC >= 0.5. Features sorted by p-value in severe patients. 63 (85%) 68 (92%)

Phosphoproteomics and proteomics study of CoV-2 infected Caco-2 cells.

 IsOMICS Phosphoproteome and Proteome,  SampleType in vitro,  CellType Caco-2,  VirusStrain SARS-CoV-2,  Timepoints 24h,  Perturbations ,  HasCompleteData ,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined904       795 (88%)
COVID234 Phosphoproteome_Klann_Caco-2_24h_Down 300 Phosphoproteome Caco-2 SARS-CoV-2 Mock 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.05. Features sorted by pvalue. 63 (21%) 266 (89%)
COVID235 Phosphoproteome_Klann_Caco-2_24h_Up 300 Phosphoproteome Caco-2 SARS-CoV-2 Mock 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.05. Features sorted by pvalue. 45 (15%) 262 (87%)
COVID236 Proteome_Klann_Caco-2_24h_Down 300 Proteome Caco-2 SARS-CoV-2 Mock 24h Significance defined by Abs(Log2FC)>0.5 and Adj P<0.05. Features sorted by pvalue. 32 (11%) 268 (89%)
COVID237 Proteome_Klann_Caco-2_24h_Up 76 Proteome Caco-2 SARS-CoV-2 Mock 24h Significance defined by Abs(Log2FC)>0.5 and Adj P<0.05. Features sorted by pvalue. 3 (4%) 67 (88%)

Processed RNAseq data from mock-infected and SARS-CoV-2 infected Vero E6 cells (MOI=0.3) collected 24 hpi (“RNAseq_Vero E6”).

 IsOMICS RNA-seq,  SampleType in vitro,  CellType Vero-E6 cells,  VirusStrain SARS-CoV-2 USA-WA1/2020,  Timepoints 24h,  Perturbations ,  HasCompleteData ,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined380       333 (88%)
COVID242 RNA_Riva_Vero-E6_24h_Down 80 RNA-seq Vero-E6 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.01. Features sorted by pvalue. 0 (0%) 57 (71%)
COVID243 RNA_Riva_Vero-E6_24h_Up 300 RNA-seq Vero-E6 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.01. Features sorted by pvalue. 0 (0%) 276 (92%)

5. Bojkova et al. SARS-CoV-2 infected host cell proteomics reveal potential therapy targets Nature peer reviewed (pre-proof)
Proteome and Translatome of SARS-CoV-2 infected CaCo-2 cells.
Extracted lists from supplement tables 1 & 2 (FC > 1.5, pvalue<0.05)
 IsOMICS Proteomics (abundance),  SampleType in vitro,  CellType CaCo-2,  VirusStrain SARS-CoV-2, clinical isolates, not specified,  Timepoints 2, 6, 10, 24 h,  Perturbations ,  HasCompleteData yes,  GeneListSource .

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined453       387 (85%)
COVID218 Proteome_Bojkova_Caco-2_10h_Down 13 Proteome Caco-2 SARS-CoV-2 Control 10h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 6 (46%) 9 (69%)
COVID219 Proteome_Bojkova_Caco-2_10h_Up 3 Proteome Caco-2 SARS-CoV-2 Control 10h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 2 (67%) 2 (67%)
COVID220 Proteome_Bojkova_Caco-2_24h_Down 72 Proteome Caco-2 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 24 (33%) 67 (93%)
COVID221 Proteome_Bojkova_Caco-2_24h_Up 42 Proteome Caco-2 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 9 (21%) 30 (71%)
COVID222 Proteome_Bojkova_Caco-2_2h_Down 3 Proteome Caco-2 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 1 (33%) 0 (0%)
COVID223 Proteome_Bojkova_Caco-2_2h_Up 2 Proteome Caco-2 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 2 (100%) 1 (50%)
COVID224 Proteome_Bojkova_Caco-2_6h_Down 3 Proteome Caco-2 SARS-CoV-2 Control 6h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 1 (33%) 2 (67%)
COVID225 Proteome_Bojkova_Caco-2_6h_Up 51 Proteome Caco-2 SARS-CoV-2 Control 6h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 13 (25%) 40 (78%)
COVID226 Translatome_Bojkova_Caco-2_10h_Down 83 Translatome Caco-2 SARS-CoV-2 Control 10h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 32 (39%) 70 (84%)
COVID227 Translatome_Bojkova_Caco-2_10h_Up 1 Translatome Caco-2 SARS-CoV-2 Control 10h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 0 (0%) 1 (100%)
COVID228 Translatome_Bojkova_Caco-2_24h_Down 170 Translatome Caco-2 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 45 (26%) 151 (89%)
COVID229 Translatome_Bojkova_Caco-2_24h_Up 44 Translatome Caco-2 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 5 (11%) 39 (89%)
COVID230 Translatome_Bojkova_Caco-2_2h_Down 18 Translatome Caco-2 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 12 (67%) 17 (94%)
COVID231 Translatome_Bojkova_Caco-2_2h_Up 13 Translatome Caco-2 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 3 (23%) 11 (85%)
COVID232 Translatome_Bojkova_Caco-2_6h_Down 18 Translatome Caco-2 SARS-CoV-2 Control 6h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 3 (17%) 14 (78%)
COVID233 Translatome_Bojkova_Caco-2_6h_Up 3 Translatome Caco-2 SARS-CoV-2 Control 6h Significance defined by Abs(Log2FC)>0.585 and P<0.05. Features sorted by pvalue. 3 (100%) 3 (100%)

Calu-3 infection with SARS-CoV-2, SARS-CoV, and MERS-CoV.
Only SARS-CoV-2 results available in supplement
 IsOMICS RNA-Seq,  SampleType in vitro,  CellType Calu-3,  VirusStrain SARS-CoV-2, MERS CoV, SARS-CoV ,  Timepoints 7, 12, 24 h,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1303       1108 (85%)
COVID035 RNA_Sun_Calu-3_0h_Down 171 RNA-seq Calu-3 SARS-CoV-2 uninfected 0h 9 (5%) 93 (54%)
COVID036 RNA_Sun_Calu-3_0h_Up 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 0h 87 (29%) 271 (90%)
COVID037 RNA_Sun_Calu-3_12h_Down 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 12h 130 (43%) 275 (92%)
COVID038 RNA_Sun_Calu-3_12h_Up 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 12h 199 (66%) 268 (89%)
COVID039 RNA_Sun_Calu-3_24h_Down 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 24h 131 (44%) 273 (91%)
COVID040 RNA_Sun_Calu-3_24h_Up 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 24h 192 (64%) 275 (92%)
COVID041 RNA_Sun_Calu-3_7h_Down 11 RNA-seq Calu-3 SARS-CoV-2 uninfected 7h 1 (9%) 9 (82%)
COVID042 RNA_Sun_Calu-3_7h_Up 63 RNA-seq Calu-3 SARS-CoV-2 uninfected 7h 57 (90%) 61 (97%)


 IsOMICS ,  SampleType patient samples,  CellType ,  VirusStrain ,  Timepoints n/a,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1043       883 (85%)
COVID244 RNA_Wilk_CD14+Monocytes_patient-C1A-mild_Up 80 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 80 (100%) 80 (100%)
COVID245 RNA_Wilk_CD14+Monocytes_patient-C1A-mild_Down 55 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 53 (96%) 52 (95%)
COVID246 RNA_Wilk_CD14+Monocytes_patient-C1B-severe_Up 77 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 75 (97%) 75 (97%)
COVID247 RNA_Wilk_CD14+Monocytes_patient-C1B-severe_Down 58 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 58 (100%) 57 (98%)
COVID248 RNA_Wilk_CD14+Monocytes_patient-C2_Up 63 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 58 (92%) 61 (97%)
COVID249 RNA_Wilk_CD14+Monocytes_patient-C2_Down 62 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 59 (95%) 55 (89%)
COVID250 RNA_Wilk_CD14+Monocytes_patient-C3_Up 51 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 49 (96%) 49 (96%)
COVID251 RNA_Wilk_CD14+Monocytes_patient-C3_Down 58 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 58 (100%) 55 (95%)
COVID252 RNA_Wilk_CD14+Monocytes_patient-C4_Up 78 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 78 (100%) 76 (97%)
COVID253 RNA_Wilk_CD14+Monocytes_patient-C4_Down 97 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 92 (95%) 89 (92%)
COVID254 RNA_Wilk_CD14+Monocytes_patient-C5_Up 104 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 101 (97%) 99 (95%)
COVID255 RNA_Wilk_CD14+Monocytes_patient-C5_Down 142 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 113 (80%) 131 (92%)
COVID256 RNA_Wilk_CD14+Monocytes_patient-C6_Up 154 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 137 (89%) 143 (93%)
COVID257 RNA_Wilk_CD14+Monocytes_patient-C6_Down 86 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 80 (93%) 81 (94%)
COVID258 RNA_Wilk_CD14+Monocytes_patient-C7_Up 32 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 29 (91%) 29 (91%)
COVID259 RNA_Wilk_CD14+Monocytes_patient-C7_Down 33 scRNA-seq CD14+ Monocytes SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 33 (100%) 30 (91%)
COVID260 RNA_Wilk_CD16+Monocytes_patient-C1A-mild_Up 74 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 66 (89%) 70 (95%)
COVID261 RNA_Wilk_CD16+Monocytes_patient-C1A-mild_Down 17 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 17 (100%) 16 (94%)
COVID262 RNA_Wilk_CD16+Monocytes_patient-C1B-severe_Up 49 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 43 (88%) 48 (98%)
COVID263 RNA_Wilk_CD16+Monocytes_patient-C1B-severe_Down 12 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 12 (100%) 12 (100%)
COVID264 RNA_Wilk_CD16+Monocytes_patient-C3_Up 39 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 35 (90%) 36 (92%)
COVID265 RNA_Wilk_CD16+Monocytes_patient-C3_Down 1 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 1 (100%) 1 (100%)
COVID266 RNA_Wilk_CD16+Monocytes_patient-C4_Up 77 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 71 (92%) 77 (100%)
COVID267 RNA_Wilk_CD16+Monocytes_patient-C4_Down 16 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 16 (100%) 15 (94%)
COVID268 RNA_Wilk_CD16+Monocytes_patient-C5_Up 100 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 72 (72%) 91 (91%)
COVID269 RNA_Wilk_CD16+Monocytes_patient-C5_Down 6 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 6 (100%) 6 (100%)
COVID270 RNA_Wilk_CD16+Monocytes_patient-C6_Up 29 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 25 (86%) 26 (90%)
COVID271 RNA_Wilk_CD16+Monocytes_patient-C7_Up 26 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 26 (100%) 26 (100%)
COVID272 RNA_Wilk_CD16+Monocytes_patient-C7_Down 27 scRNA-seq CD16+ Monocytes SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 20 (74%) 24 (89%)
COVID273 RNA_Wilk_Dendritic-cells_patient-C1A-mild_Up 40 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 40 (100%) 40 (100%)
COVID274 RNA_Wilk_Dendritic-cells_patient-C1A-mild_Down 1 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 1 (100%) 1 (100%)
COVID275 RNA_Wilk_Dendritic-cells_patient-C1B-severe_Up 15 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 14 (93%) 15 (100%)
COVID276 RNA_Wilk_Dendritic-cells_patient-C1B-severe_Down 1 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 1 (100%) 1 (100%)
COVID277 RNA_Wilk_Dendritic-cells_patient-C2_Up 72 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 3 (4%) 33 (46%)
COVID278 RNA_Wilk_Dendritic-cells_patient-C3_Up 11 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 11 (100%) 9 (82%)
COVID279 RNA_Wilk_Dendritic-cells_patient-C3_Down 1 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 1 (100%) 1 (100%)
COVID280 RNA_Wilk_Dendritic-cells_patient-C4_Up 25 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 25 (100%) 25 (100%)
COVID281 RNA_Wilk_Dendritic-cells_patient-C4_Down 18 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 18 (100%) 16 (89%)
COVID282 RNA_Wilk_Dendritic-cells_patient-C5_Up 73 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 67 (92%) 72 (99%)
COVID283 RNA_Wilk_Dendritic-cells_patient-C5_Down 22 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 21 (95%) 20 (91%)
COVID284 RNA_Wilk_Dendritic-cells_patient-C6_Up 16 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 12 (75%) 12 (75%)
COVID285 RNA_Wilk_Dendritic-cells_patient-C7_Up 29 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 27 (93%) 27 (93%)
COVID286 RNA_Wilk_Dendritic-cells_patient-C7_Down 26 scRNA-seq Dendritic cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 21 (81%) 24 (92%)
COVID287 RNA_Wilk_NK-cells_patient-C1A-mild_Up 34 scRNA-seq NK cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 34 (100%) 32 (94%)
COVID288 RNA_Wilk_NK-cells_patient-C1A-mild_Down 16 scRNA-seq NK cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 16 (100%) 15 (94%)
COVID289 RNA_Wilk_NK-cells_patient-C1B-severe_Up 12 scRNA-seq NK cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 8 (67%) 8 (67%)
COVID290 RNA_Wilk_NK-cells_patient-C1B-severe_Down 14 scRNA-seq NK cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 14 (100%) 12 (86%)
COVID291 RNA_Wilk_NK-cells_patient-C2_Up 5 scRNA-seq NK cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 4 (80%) 4 (80%)
COVID292 RNA_Wilk_NK-cells_patient-C2_Down 7 scRNA-seq NK cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 5 (71%) 7 (100%)
COVID293 RNA_Wilk_NK-cells_patient-C3_Up 25 scRNA-seq NK cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 23 (92%) 24 (96%)
COVID294 RNA_Wilk_NK-cells_patient-C3_Down 8 scRNA-seq NK cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 8 (100%) 7 (88%)
COVID295 RNA_Wilk_NK-cells_patient-C4_Up 24 scRNA-seq NK cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 23 (96%) 23 (96%)
COVID296 RNA_Wilk_NK-cells_patient-C4_Down 22 scRNA-seq NK cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 22 (100%) 21 (95%)
COVID297 RNA_Wilk_NK-cells_patient-C5_Up 52 scRNA-seq NK cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 43 (83%) 48 (92%)
COVID298 RNA_Wilk_NK-cells_patient-C5_Down 29 scRNA-seq NK cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 26 (90%) 27 (93%)
COVID299 RNA_Wilk_NK-cells_patient-C6_Up 30 scRNA-seq NK cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 28 (93%) 30 (100%)
COVID300 RNA_Wilk_NK-cells_patient-C6_Down 4 scRNA-seq NK cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 4 (100%) 4 (100%)
COVID301 RNA_Wilk_NK-cells_patient-C7_Up 5 scRNA-seq NK cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 5 (100%) 5 (100%)
COVID302 RNA_Wilk_NK-cells_patient-C7_Down 30 scRNA-seq NK cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 20 (67%) 27 (90%)
COVID303 RNA_Wilk_CD8+T-cells_patient-C1A-mild_Up 19 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 19 (100%) 19 (100%)
COVID304 RNA_Wilk_CD8+T-cells_patient-C1A-mild_Down 22 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 20 (91%) 18 (82%)
COVID305 RNA_Wilk_CD8+T-cells_patient-C1B-severe_Up 10 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 10 (100%) 9 (90%)
COVID306 RNA_Wilk_CD8+T-cells_patient-C1B-severe_Down 9 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 9 (100%) 8 (89%)
COVID307 RNA_Wilk_CD8+T-cells_patient-C2_Up 10 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 10 (100%) 9 (90%)
COVID308 RNA_Wilk_CD8+T-cells_patient-C2_Down 10 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 9 (90%) 9 (90%)
COVID309 RNA_Wilk_CD8+T-cells_patient-C3_Up 33 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 31 (94%) 31 (94%)
COVID310 RNA_Wilk_CD8+T-cells_patient-C3_Down 5 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 5 (100%) 5 (100%)
COVID311 RNA_Wilk_CD8+T-cells_patient-C4_Up 22 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 22 (100%) 22 (100%)
COVID312 RNA_Wilk_CD8+T-cells_patient-C4_Down 31 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 31 (100%) 31 (100%)
COVID313 RNA_Wilk_CD8+T-cells_patient-C5_Up 43 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 41 (95%) 42 (98%)
COVID314 RNA_Wilk_CD8+T-cells_patient-C5_Down 45 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 39 (87%) 41 (91%)
COVID315 RNA_Wilk_CD8+T-cells_patient-C6_Up 41 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 37 (90%) 40 (98%)
COVID316 RNA_Wilk_CD8+T-cells_patient-C6_Down 11 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 11 (100%) 11 (100%)
COVID317 RNA_Wilk_CD8+T-cells_patient-C7_Up 3 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 3 (100%) 2 (67%)
COVID318 RNA_Wilk_CD8+T-cells_patient-C7_Down 12 scRNA-seq CD8+ T cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 10 (83%) 10 (83%)
COVID319 RNA_Wilk_CD4+T-cells_patient-C1A-mild_Up 40 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 40 (100%) 40 (100%)
COVID320 RNA_Wilk_CD4+T-cells_patient-C1A-mild_Down 34 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 33 (97%) 31 (91%)
COVID321 RNA_Wilk_CD4+T-cells_patient-C1B-severe_Up 13 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 13 (100%) 13 (100%)
COVID322 RNA_Wilk_CD4+T-cells_patient-C1B-severe_Down 7 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 7 (100%) 7 (100%)
COVID323 RNA_Wilk_CD4+T-cells_patient-C2_Up 21 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 18 (86%) 20 (95%)
COVID324 RNA_Wilk_CD4+T-cells_patient-C2_Down 10 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 10 (100%) 9 (90%)
COVID325 RNA_Wilk_CD4+T-cells_patient-C3_Up 15 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 14 (93%) 15 (100%)
COVID326 RNA_Wilk_CD4+T-cells_patient-C3_Down 6 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 6 (100%) 6 (100%)
COVID327 RNA_Wilk_CD4+T-cells_patient-C4_Up 24 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 24 (100%) 24 (100%)
COVID328 RNA_Wilk_CD4+T-cells_patient-C4_Down 31 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 30 (97%) 29 (94%)
COVID329 RNA_Wilk_CD4+T-cells_patient-C5_Up 38 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 38 (100%) 38 (100%)
COVID330 RNA_Wilk_CD4+T-cells_patient-C5_Down 32 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 31 (97%) 29 (91%)
COVID331 RNA_Wilk_CD4+T-cells_patient-C6_Up 38 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 32 (84%) 35 (92%)
COVID332 RNA_Wilk_CD4+T-cells_patient-C6_Down 12 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 11 (92%) 11 (92%)
COVID333 RNA_Wilk_CD4+T-cells_patient-C7_Up 8 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 7 (88%) 7 (88%)
COVID334 RNA_Wilk_CD4+T-cells_patient-C7_Down 11 scRNA-seq CD4+ T cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 10 (91%) 10 (91%)
COVID335 RNA_Wilk_B-cells_patient-C1A-mild_Up 63 scRNA-seq B cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 63 (100%) 62 (98%)
COVID336 RNA_Wilk_B-cells_patient-C1A-mild_Down 60 scRNA-seq B cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 60 (100%) 52 (87%)
COVID337 RNA_Wilk_B-cells_patient-C1B-severe_Up 104 scRNA-seq B cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 97 (93%) 95 (91%)
COVID338 RNA_Wilk_B-cells_patient-C1B-severe_Down 76 scRNA-seq B cells SARS-CoV-2 Healthy 11d post onset SARS-CoV-2 patient C1, male, 60-69 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 17. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 76 (100%) 70 (92%)
COVID339 RNA_Wilk_B-cells_patient-C2_Up 34 scRNA-seq B cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 33 (97%) 34 (100%)
COVID340 RNA_Wilk_B-cells_patient-C2_Down 19 scRNA-seq B cells SARS-CoV-2 Healthy 16d post onset SARS-CoV-2 patient C2, male, 40-49 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 19 (100%) 17 (89%)
COVID341 RNA_Wilk_B-cells_patient-C3_Up 82 scRNA-seq B cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 80 (98%) 78 (95%)
COVID342 RNA_Wilk_B-cells_patient-C3_Down 28 scRNA-seq B cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C3, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 25. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 28 (100%) 26 (93%)
COVID343 RNA_Wilk_B-cells_patient-C4_Up 121 scRNA-seq B cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 104 (86%) 114 (94%)
COVID344 RNA_Wilk_B-cells_patient-C4_Down 169 scRNA-seq B cells SARS-CoV-2 Healthy 9d post onset SARS-CoV-2 patient C4, male, 30-39 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 16. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 166 (98%) 147 (87%)
COVID345 RNA_Wilk_B-cells_patient-C5_Up 116 scRNA-seq B cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 107 (92%) 110 (95%)
COVID346 RNA_Wilk_B-cells_patient-C5_Down 181 scRNA-seq B cells SARS-CoV-2 Healthy 15d post onset SARS-CoV-2 patient C5, male, 50-59 yr, ventilated/ARDS: no, admission level: ICU, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 164 (91%) 157 (87%)
COVID347 RNA_Wilk_B-cells_patient-C6_Up 110 scRNA-seq B cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 51 (46%) 100 (91%)
COVID348 RNA_Wilk_B-cells_patient-C6_Down 33 scRNA-seq B cells SARS-CoV-2 Healthy 2d post onset SARS-CoV-2 patient C6, male, >80 yr, ventilated/ARDS: yes, admission level: ICU, days intubated: 11. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 33 (100%) 32 (97%)
COVID349 RNA_Wilk_B-cells_patient-C7_Up 5 scRNA-seq B cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 5 (100%) 5 (100%)
COVID350 RNA_Wilk_B-cells_patient-C7_Down 39 scRNA-seq B cells SARS-CoV-2 Healthy 12d post onset SARS-CoV-2 patient C7, male, 20-29 yr, ventilated/ARDS: no, admission level: floor, days intubated: 0. Singificance defined by p-value < 0.05 and abs(log2FC) >= 0.25. Features sorted by log2FC. 37 (95%) 36 (92%)

Nasopharyngeal swabs from 430 SARS-CoV-2 patients and 54 controls.

 IsOMICS RNA-seq,  SampleType patient samples,  CellType SARS CoV2 patients,  VirusStrain SARS-CoV2,  Timepoints n/a,  Perturbations ,  HasCompleteData ,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined414       350 (85%)
COVID238 RNA_Lieberman_Nasopharynx_Infected_vs_Neg_Down 42 RNA-seq Nasopharynx SARS-CoV-2 Negative Significance defined by Abs(Log2FC)>1 and Adj P<0.1. Features sorted by pvalue. 8 (19%) 41 (98%)
COVID239 RNA_Lieberman_Nasopharynx_Infected_vs_Neg_Up 41 RNA-seq Nasopharynx SARS-CoV-2 Negative Significance defined by Abs(Log2FC)>1 and Adj P<0.1. Features sorted by pvalue. 22 (54%) 39 (95%)
COVID240 RNA_Lieberman_Nasopharynx_High_vs_Low_Down 188 RNA-seq Nasopharynx SARS-CoV-2 High Viral Load SARS-CoV-2 Low Viral Load Significance defined by Adj P<0.1. Features sorted by pvalue. 9 (5%) 153 (81%)
COVID241 RNA_Lieberman_Nasopharynx_High_vs_Low_Up 173 RNA-seq Nasopharynx SARS-CoV-2 High Viral Load SARS-CoV-2 Low Viral Load Significance defined by Adj P<0.1. Features sorted by pvalue. 21 (12%) 146 (84%)

Phosphoproteomics study of CoV-2 infected Vero-E6 cells.

 IsOMICS Phosphoproteomics,  SampleType in vitro,  CellType Vero-E6 cells,  VirusStrain SARS-CoV2,  Timepoints 0 to 24h,  Perturbations ,  HasCompleteData ,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1264       1054 (83%)
COVID055 Phosphoproteome_Bouhaddou_Vero_E6_0h_Down 277 Phosphoproteome Vero_E6 SARS-CoV-2 Control 0h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 217 (78%) 238 (86%)
COVID056 Phosphoproteome_Bouhaddou_Vero_E6_0h_Up 184 Phosphoproteome Vero_E6 SARS-CoV-2 Control 0h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 145 (79%) 160 (87%)
COVID057 Phosphoproteome_Bouhaddou_Vero_E6_12h_Down 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 12h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 290 (97%) 260 (87%)
COVID058 Phosphoproteome_Bouhaddou_Vero_E6_12h_Up 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 12h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 277 (92%) 254 (85%)
COVID059 Phosphoproteome_Bouhaddou_Vero_E6_24h_Down 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 254 (85%) 254 (85%)
COVID060 Phosphoproteome_Bouhaddou_Vero_E6_24h_Up 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 230 (77%) 256 (85%)
COVID061 Phosphoproteome_Bouhaddou_Vero_E6_2h_Down 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 249 (83%) 255 (85%)
COVID062 Phosphoproteome_Bouhaddou_Vero_E6_2h_Up 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 272 (91%) 252 (84%)
COVID063 Phosphoproteome_Bouhaddou_Vero_E6_4h_Down 197 Phosphoproteome Vero_E6 SARS-CoV-2 Control 4h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 187 (95%) 171 (87%)
COVID064 Phosphoproteome_Bouhaddou_Vero_E6_4h_Up 262 Phosphoproteome Vero_E6 SARS-CoV-2 Control 4h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 245 (94%) 217 (83%)
COVID065 Phosphoproteome_Bouhaddou_Vero_E6_8h_Down 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 8h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 276 (92%) 263 (88%)
COVID066 Phosphoproteome_Bouhaddou_Vero_E6_8h_Up 300 Phosphoproteome Vero_E6 SARS-CoV-2 Control 8h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 280 (93%) 252 (84%)
COVID067 Proteome_Bouhaddou_Vero_E6_0h_Down 10 Proteome Vero_E6 SARS-CoV-2 Control 0h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 4 (40%) 9 (90%)
COVID068 Proteome_Bouhaddou_Vero_E6_0h_Up 1 Proteome Vero_E6 SARS-CoV-2 Control 0h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 0 (0%) 1 (100%)
COVID069 Proteome_Bouhaddou_Vero_E6_12h_Down 52 Proteome Vero_E6 SARS-CoV-2 Control 12h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 49 (94%) 49 (94%)
COVID070 Proteome_Bouhaddou_Vero_E6_12h_Up 6 Proteome Vero_E6 SARS-CoV-2 Control 12h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 6 (100%) 3 (50%)
COVID071 Proteome_Bouhaddou_Vero_E6_24h_Down 95 Proteome Vero_E6 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 60 (63%) 86 (91%)
COVID072 Proteome_Bouhaddou_Vero_E6_24h_Up 15 Proteome Vero_E6 SARS-CoV-2 Control 24h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 7 (47%) 9 (60%)
COVID073 Proteome_Bouhaddou_Vero_E6_2h_Down 42 Proteome Vero_E6 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 39 (93%) 39 (93%)
COVID074 Proteome_Bouhaddou_Vero_E6_2h_Up 6 Proteome Vero_E6 SARS-CoV-2 Control 2h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 4 (67%) 3 (50%)
COVID075 Proteome_Bouhaddou_Vero_E6_4h_Down 32 Proteome Vero_E6 SARS-CoV-2 Control 4h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 32 (100%) 29 (91%)
COVID076 Proteome_Bouhaddou_Vero_E6_4h_Up 3 Proteome Vero_E6 SARS-CoV-2 Control 4h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 3 (100%) 0 (0%)
COVID077 Proteome_Bouhaddou_Vero_E6_8h_Down 44 Proteome Vero_E6 SARS-CoV-2 Control 8h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 41 (93%) 41 (93%)
COVID078 Proteome_Bouhaddou_Vero_E6_8h_Up 6 Proteome Vero_E6 SARS-CoV-2 Control 8h Significance defined by Abs(Log2FC)>1 and Adj P<0.05 as in the publication. Features sorted by pvalue. 5 (83%) 3 (50%)

SARS-CoV-2-Human Protein-Protein Interaction Map.

 IsOMICS Proteomics (APMS),  SampleType in vitro,  CellType HEK293T,  VirusStrain SARS-CoV-2 (USA-WA1/2020),  Timepoints n/a,  Perturbations ,  HasCompleteData yes,  GeneListSource .

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined332       270 (81%)
COVID081 Interactome_Gordon_HEK-293T_38h_E 6 Interactome HEK-293T E 38h 0 (0%) 5 (83%)
COVID082 Interactome_Gordon_HEK-293T_38h_M 30 Interactome HEK-293T M 38h 0 (0%) 24 (80%)
COVID083 Interactome_Gordon_HEK-293T_38h_N 15 Interactome HEK-293T N 38h 0 (0%) 14 (93%)
COVID084 Interactome_Gordon_HEK-293T_38h_NSP1 6 Interactome HEK-293T NSP1 38h 0 (0%) 6 (100%)
COVID085 Interactome_Gordon_HEK-293T_38h_NSP10 5 Interactome HEK-293T NSP10 38h 0 (0%) 4 (80%)
COVID086 Interactome_Gordon_HEK-293T_38h_NSP11 1 Interactome HEK-293T NSP11 38h 0 (0%) 0 (0%)
COVID087 Interactome_Gordon_HEK-293T_38h_NSP12 20 Interactome HEK-293T NSP12 38h 0 (0%) 17 (85%)
COVID088 Interactome_Gordon_HEK-293T_38h_NSP13 40 Interactome HEK-293T NSP13 38h 0 (0%) 26 (65%)
COVID089 Interactome_Gordon_HEK-293T_38h_NSP14 3 Interactome HEK-293T NSP14 38h 0 (0%) 3 (100%)
COVID090 Interactome_Gordon_HEK-293T_38h_NSP15 3 Interactome HEK-293T NSP15 38h 0 (0%) 2 (67%)
COVID091 Interactome_Gordon_HEK-293T_38h_NSP2 7 Interactome HEK-293T NSP2 38h 0 (0%) 7 (100%)
COVID092 Interactome_Gordon_HEK-293T_38h_NSP4 8 Interactome HEK-293T NSP4 38h 0 (0%) 7 (88%)
COVID093 Interactome_Gordon_HEK-293T_38h_NSP5 1 Interactome HEK-293T NSP5 38h 0 (0%) 1 (100%)
COVID094 Interactome_Gordon_HEK-293T_38h_NSP5_C145A 2 Interactome HEK-293T NSP5_C145A 38h 0 (0%) 1 (50%)
COVID095 Interactome_Gordon_HEK-293T_38h_NSP6 4 Interactome HEK-293T NSP6 38h 0 (0%) 3 (75%)
COVID096 Interactome_Gordon_HEK-293T_38h_NSP7 32 Interactome HEK-293T NSP7 38h 0 (0%) 27 (84%)
COVID097 Interactome_Gordon_HEK-293T_38h_NSP8 24 Interactome HEK-293T NSP8 38h 0 (0%) 19 (79%)
COVID098 Interactome_Gordon_HEK-293T_38h_NSP9 16 Interactome HEK-293T NSP9 38h 0 (0%) 15 (94%)
COVID099 Interactome_Gordon_HEK-293T_38h_ORF10 9 Interactome HEK-293T ORF10 38h 0 (0%) 9 (100%)
COVID100 Interactome_Gordon_HEK-293T_38h_ORF3A 8 Interactome HEK-293T ORF3A 38h 0 (0%) 8 (100%)
COVID101 Interactome_Gordon_HEK-293T_38h_ORF3B 1 Interactome HEK-293T ORF3B 38h 0 (0%) 1 (100%)
COVID102 Interactome_Gordon_HEK-293T_38h_ORF6 3 Interactome HEK-293T ORF6 38h 0 (0%) 3 (100%)
COVID103 Interactome_Gordon_HEK-293T_38h_ORF7A 2 Interactome HEK-293T ORF7A 38h 0 (0%) 2 (100%)
COVID104 Interactome_Gordon_HEK-293T_38h_ORF8 47 Interactome HEK-293T ORF8 38h 0 (0%) 33 (70%)
COVID105 Interactome_Gordon_HEK-293T_38h_ORF9B 11 Interactome HEK-293T ORF9B 38h 0 (0%) 11 (100%)
COVID106 Interactome_Gordon_HEK-293T_38h_ORF9C 26 Interactome HEK-293T ORF9C 38h 0 (0%) 20 (77%)
COVID107 Interactome_Gordon_HEK-293T_38h_S 2 Interactome HEK-293T S 38h 0 (0%) 2 (100%)

11. Lamers et al. SARS-CoV-2 productively infects human gut enterocytes Science peer reviewed
Bulk RNA sequencing of SARS-CoV and SARS-CoV-2 infected human intestinal organoids.

 IsOMICS RNA-Seq,  SampleType in vitro,  CellType human intestinal organoids,  VirusStrain SARS-CoV-2,  Timepoints 24, 60 h,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined477       379 (79%)
COVID025 RNA_Lamers_intestinal-organoid_differentiated_Down 46 RNA-seq intestinal organoid (differentiation medium) SARS-CoV-2 uninfected 60h 22 (48%) 36 (78%)
COVID026 RNA_Lamers_intestinal-organoid_differentiated_Up 36 RNA-seq intestinal organoid (differentiation medium) SARS-CoV-2 uninfected 60h 14 (39%) 28 (78%)
COVID027 RNA_Lamers_intestinal-organoid_expansion_Down 264 RNA-seq intestinal-organoid (expansion medium) SARS-CoV-2 uninfected 60h 20 (8%) 208 (79%)
COVID028 RNA_Lamers_intestinal-organoid_expansion_Up 167 RNA-seq intestinal-organoid (expansion medium) SARS-CoV-2 uninfected 60h 16 (10%) 139 (83%)

12. Blanco-Melo et al. Imbalanced host response to SARS-CoV-2 drives development of COVID-19 Cell peer reviewed (pre-proof)

 IsOMICS RNA-Seq,  SampleType in vitro, in vivo model, patient samples,  CellType primary human lung epithelium (NHBE), A549, Calu-3, ferrets, patient samples,  VirusStrain SARS-CoV-2 (USA-WA1/2020),  Timepoints multiple, depending on model system,  Perturbations ,  HasCompleteData yes,  GeneListSource GEO read counts.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1793       1424 (79%)
COVID007 RNA_Blanco-Melo_A549_Down 300 RNA-seq A549 SARS-CoV-2 uninfected 9h 139 (46%) 240 (80%)
COVID008 RNA_Blanco-Melo_A549_Up 300 RNA-seq A549 SARS-CoV-2 uninfected 9h 108 (36%) 249 (83%)
COVID009 RNA_Blanco-Melo_A549-ACE2_Down 207 RNA-seq A549 w/ exogenous ACE2 SARS-CoV-2 uninfected 9h 54 (26%) 165 (80%)
COVID010 RNA_Blanco-Melo_A549-ACE2_Up 300 RNA-seq A549 w/ exogenous ACE2 SARS-CoV-2 uninfected 9h 90 (30%) 237 (79%)
COVID011 RNA_Blanco-Melo_A549-ACE2-ruxolitinib_Down 233 RNA-seq A549 w/ exogenous ACE2 SARS-CoV-2 and ruxolitinib SARS-CoV-2 9h 142 (61%) 210 (90%)
COVID012 RNA_Blanco-Melo_A549-ACE2-ruxolitinib_Up 8 RNA-seq A549 w/ exogenous ACE2 SARS-CoV-2 and ruxolitinib SARS-CoV-2 9h 5 (62%) 6 (75%)
COVID013 RNA_Blanco-Melo_A549-low-MOI_Down 1 RNA-seq A549 SARS-CoV-2 (low MOI) uninfected 9h 1 (100%) 1 (100%)
COVID014 RNA_Blanco-Melo_A549-low-MOI_Up 35 RNA-seq A549 SARS-CoV-2 (low MOI) uninfected 9h 35 (100%) 35 (100%)
COVID015 RNA_Blanco-Melo_Calu-3_Down 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 9h 131 (44%) 247 (82%)
COVID016 RNA_Blanco-Melo_Calu-3_Up 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 9h 219 (73%) 288 (96%)
COVID017 RNA_Blanco-Melo_Lung_Down 259 RNA-seq Lung SARS-CoV-2 uninfected post-mortem 73 (28%) 185 (71%)
COVID018 RNA_Blanco-Melo_Lung_Up 83 RNA-seq Lung SARS-CoV-2 uninfected post-mortem 23 (28%) 64 (77%)
COVID019 RNA_Blanco-Melo_NHBE_Down 11 RNA-seq NHBE SARS-CoV-2 uninfected 24h 1 (9%) 8 (73%)
COVID020 RNA_Blanco-Melo_NHBE_Up 85 RNA-seq NHBE SARS-CoV-2 uninfected 24h 62 (73%) 78 (92%)

Gene expression profiling of SARS-CoV-1/2 infected human cell lines at bulk and single-cell level.
Includes small RNA-seq in addition to polyA/total RNA. H1299 cell line ignored since few genes change overall.
 IsOMICS RNA-Seq, scRNA-seq,  SampleType in vitro,  CellType Calu-3, Caco-2, H1299,  VirusStrain SARS-CoV-2,  Timepoints 4, 8, 12, 24, 36 h,  Perturbations ,  HasCompleteData Yes,  GeneListSource GEO read counts.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1033       820 (79%)
COVID043 RNA_Wyler_Caco-2_12h_Down 123 RNA-seq Caco-2 SARS-CoV-2 uninfected 12h 37 (30%) 83 (67%)
COVID044 RNA_Wyler_Caco-2_12h_Up 28 RNA-seq Caco-2 SARS-CoV-2 uninfected 12h 17 (61%) 22 (79%)
COVID045 RNA_Wyler_Caco-2_24h_Down 32 RNA-seq Caco-2 SARS-CoV-2 uninfected 24h 20 (62%) 24 (75%)
COVID046 RNA_Wyler_Caco-2_24h_Up 95 RNA-seq Caco-2 SARS-CoV-2 uninfected 24h 39 (41%) 78 (82%)
COVID047 RNA_Wyler_Calu-3_12h_Down 188 RNA-seq Calu-3 SARS-CoV-2 uninfected 12h 42 (22%) 120 (64%)
COVID048 RNA_Wyler_Calu-3_12h_Up 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 12h 215 (72%) 290 (97%)
COVID049 RNA_Wyler_Calu-3_24h_Down 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 24h 50 (17%) 225 (75%)
COVID050 RNA_Wyler_Calu-3_24h_Up 300 RNA-seq Calu-3 SARS-CoV-2 uninfected 24h 219 (73%) 287 (96%)

Proteomics comparison of sera samples from healthy, severe and non-severe COVID-19 patients, and non-COVID-19 patients.

 IsOMICS Proteomics and metabolomics,  SampleType patient and healthy samples,  CellType Healthy, non-COVID-19, and SARS CoV2 patient sera,  VirusStrain ,  Timepoints N/A,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined134       106 (79%)
COVID210 Proteome_Shen_Serum-severe-vs-nonsevere_Up 25 Proteome Serum SARS-CoV-2 (severe) SARS-CoV-2 (mild) Significance defined by Supp Table. Features sorted by pvalue. 25 (100%) 20 (80%)
COVID211 Proteome_Shen_Serum-severe-vs-nonsevere_Down 16 Proteome Serum SARS-CoV-2 (severe) SARS-CoV-2 (mild) Significance defined by Supp Table. Features sorted by pvalue. 15 (94%) 13 (81%)
COVID212 Proteome_Shen_Serum-severe-vs-healthy_Up 62 Proteome Serum SARS-CoV-2 (severe) Healthy Significance defined by Supp Table. Features sorted by pvalue. 34 (55%) 53 (85%)
COVID213 Proteome_Shen_Serum-severe-vs-healthy_Down 58 Proteome Serum SARS-CoV-2 (severe) Healthy Significance defined by Supp Table. Features sorted by pvalue. 37 (64%) 41 (71%)
COVID214 Proteome_Shen_Serum-nonCovid-vs-healthy_Up 15 Proteome Serum Non-SARS-CoV-2 patient Healthy Significance defined by Supp Table. Features sorted by pvalue. 11 (73%) 14 (93%)
COVID215 Proteome_Shen_Serum-nonCovid-vs-healthy_Down 13 Proteome Serum Non-SARS-CoV-2 patient Healthy Significance defined by Supp Table. Features sorted by pvalue. 13 (100%) 9 (69%)
COVID216 Proteome_Shen_Serum-nonsevere-vs-healthy_Up 20 Proteome Serum SARS-CoV-2 (mild) Healthy Significance defined by Supp Table. Features sorted by pvalue. 15 (75%) 16 (80%)
COVID217 Proteome_Shen_Serum-nonsevere-vs-healthy_Down 23 Proteome Serum SARS-CoV-2 (mild) Healthy Significance defined by Supp Table. Features sorted by pvalue. 20 (87%) 18 (78%)

15. Li et al. Urine Proteome of COVID-19 Patients medRxiv pre-print
Proteomics analysis of urine samples from healthy, mild, and severe COVID-19 patients.

 IsOMICS Proteomics,  SampleType patient and healthy samples,  CellType Healthy and SARS CoV2 patient urine,  VirusStrain ,  Timepoints N/A,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined491       386 (79%)
COVID204 Proteome_Li_Urine-severe-vs-healthy_Up 83 Proteome Urine SARS-CoV-2 (severe) Healthy Significance defined by Supp Table. Features sorted by pvalue. 53 (64%) 69 (83%)
COVID205 Proteome_Li_Urine-severe-vs-healthy_Down 170 Proteome Urine SARS-CoV-2 (severe) Healthy Significance defined by Supp Table. Features sorted by pvalue. 106 (62%) 126 (74%)
COVID206 Proteome_Li_Urine-mild-vs-healthy_Up 86 Proteome Urine SARS-CoV-2 (mild) Healthy Significance defined by Supp Table. Features sorted by pvalue. 54 (63%) 71 (83%)
COVID207 Proteome_Li_Urine-mild-vs-healthy_Down 99 Proteome Urine SARS-CoV-2 (mild) Healthy Significance defined by Supp Table. Features sorted by pvalue. 86 (87%) 71 (72%)
COVID208 Proteome_Li_Urine-recovery-vs-healthy_Up 152 Proteome Urine SARS-CoV-2 (in recovery) Healthy Significance defined by Supp Table. Features sorted by pvalue. 45 (30%) 125 (82%)
COVID209 Proteome_Li_Urine-recovery-vs-healthy_Down 126 Proteome Urine SARS-CoV-2 (in recovery) Healthy Significance defined by Supp Table. Features sorted by pvalue. 62 (49%) 95 (75%)

BioID interactome data in HEK293.

 IsOMICS Interactome by BioID,  SampleType in vitro,  CellType HEK293,  VirusStrain SARS-CoV-2 strain HKU-SZ-005b,  Timepoints 24h,  Perturbations ,  HasCompleteData Yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined2032       1522 (75%)
COVID363 Interactome_Laurent_HEK293_24h_E 300 Interactome HEK293 E 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 294 (98%) 235 (78%)
COVID364 Interactome_Laurent_HEK293_24h_M 300 Interactome HEK293 M 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 277 (92%) 221 (74%)
COVID365 Interactome_Laurent_HEK293_24h_N 79 Interactome HEK293 N 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 48 (61%) 54 (68%)
COVID366 Interactome_Laurent_HEK293_24h_NSP1 41 Interactome HEK293 NSP1 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 20 (49%) 35 (85%)
COVID367 Interactome_Laurent_HEK293_24h_NSP10 38 Interactome HEK293 NSP10 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 32 (84%) 26 (68%)
COVID368 Interactome_Laurent_HEK293_24h_NSP12 255 Interactome HEK293 NSP12 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 205 (80%) 173 (68%)
COVID369 Interactome_Laurent_HEK293_24h_NSP13 57 Interactome HEK293 NSP13 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 45 (79%) 49 (86%)
COVID370 Interactome_Laurent_HEK293_24h_NSP14 59 Interactome HEK293 NSP14 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 50 (85%) 45 (76%)
COVID371 Interactome_Laurent_HEK293_24h_NSP15 106 Interactome HEK293 NSP15 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 67 (63%) 79 (75%)
COVID372 Interactome_Laurent_HEK293_24h_NSP16 283 Interactome HEK293 NSP16 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 215 (76%) 207 (73%)
COVID373 Interactome_Laurent_HEK293_24h_NSP2 228 Interactome HEK293 NSP2 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 167 (73%) 162 (71%)
COVID374 Interactome_Laurent_HEK293_24h_NSP3 299 Interactome HEK293 NSP3 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 223 (75%) 228 (76%)
COVID375 Interactome_Laurent_HEK293_24h_NSP4 300 Interactome HEK293 NSP4 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 291 (97%) 216 (72%)
COVID376 Interactome_Laurent_HEK293_24h_NSP5 21 Interactome HEK293 NSP5 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 17 (81%) 15 (71%)
COVID377 Interactome_Laurent_HEK293_24h_NSP6 300 Interactome HEK293 NSP6 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 278 (93%) 237 (79%)
COVID378 Interactome_Laurent_HEK293_24h_NSP7 300 Interactome HEK293 NSP7 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 215 (72%) 201 (67%)
COVID379 Interactome_Laurent_HEK293_24h_NSP8 21 Interactome HEK293 NSP8 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 18 (86%) 19 (90%)
COVID380 Interactome_Laurent_HEK293_24h_NSP9 70 Interactome HEK293 NSP9 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 54 (77%) 59 (84%)
COVID381 Interactome_Laurent_HEK293_24h_ORF10 85 Interactome HEK293 ORF10 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 73 (86%) 73 (86%)
COVID382 Interactome_Laurent_HEK293_24h_ORF3A 300 Interactome HEK293 ORF3A 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 269 (90%) 244 (81%)
COVID383 Interactome_Laurent_HEK293_24h_ORF3B 300 Interactome HEK293 ORF3B 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 224 (75%) 235 (78%)
COVID384 Interactome_Laurent_HEK293_24h_ORF6 300 Interactome HEK293 ORF6 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 257 (86%) 231 (77%)
COVID385 Interactome_Laurent_HEK293_24h_ORF7A 300 Interactome HEK293 ORF7A 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 289 (96%) 235 (78%)
COVID386 Interactome_Laurent_HEK293_24h_ORF7B 300 Interactome HEK293 ORF7B 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 290 (97%) 227 (76%)
COVID387 Interactome_Laurent_HEK293_24h_ORF8 300 Interactome HEK293 ORF8 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 243 (81%) 240 (80%)
COVID388 Interactome_Laurent_HEK293_24h_ORF9B 111 Interactome HEK293 ORF9B 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 82 (74%) 79 (71%)
COVID389 Interactome_Laurent_HEK293_24h_ORF9C 300 Interactome HEK293 ORF9C 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 212 (71%) 237 (79%)
COVID390 Interactome_Laurent_HEK293_24h_S 300 Interactome HEK293 S 24h Performed under infection-mimicking condition for 24hrs prior proximity labeling. 285 (95%) 224 (75%)


 IsOMICS RNA-Seq,  SampleType patient samples,  CellType BALF, PBMC,  VirusStrain SARS-CoV-2,  Timepoints n/a,  Perturbations ,  HasCompleteData yes,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1146       791 (69%)
COVID051 RNA_Xiong_BALF_Down 300 RNA-seq BALF SARS-CoV-2 uninfected 3 (1%) 253 (84%)
COVID052 RNA_Xiong_BALF_Up 300 RNA-seq BALF SARS-CoV-2 uninfected 8 (3%) 221 (74%)
COVID053 RNA_Xiong_PBMC_Down 257 RNA-seq PBMC SARS-CoV-2 uninfected 7 (3%) 116 (45%)
COVID054 RNA_Xiong_PBMC_Up 300 RNA-seq PBMC SARS-CoV-2 uninfected 4 (1%) 209 (70%)

Comprehensive SARS-CoV-2 infection profiling using proteomics and RNASeq, particularly for different SARS-CoV-2 proteins.

 IsOMICS Interactome, Proteomics, Ubiquitome, Phosphoproteome, RNA-seq,  SampleType in vitro,  CellType A549-ACE2,  VirusStrain SARS-CoV-2-MUC-IMB-1,  Timepoints 6 to 72h,  Perturbations ,  HasCompleteData ,  GeneListSource Supplemental table.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined4673       3180 (68%)
COVID108 Interactome_Stukalov_A549_72h_E 11 Interactome A549 E 72h Significance defined by Supp Table. Features sorted by pvalue. 7 (64%) 6 (55%)
COVID109 Interactome_Stukalov_A549_72h_M 138 Interactome A549 M 72h Significance defined by Supp Table. Features sorted by pvalue. 67 (49%) 87 (63%)
COVID110 Interactome_Stukalov_A549_72h_N 9 Interactome A549 N 72h Significance defined by Supp Table. Features sorted by pvalue. 6 (67%) 6 (67%)
COVID111 Interactome_Stukalov_A549_72h_NSP1 3 Interactome A549 NSP1 72h Significance defined by Supp Table. Features sorted by pvalue. 3 (100%) 2 (67%)
COVID112 Interactome_Stukalov_A549_72h_NSP12 1 Interactome A549 NSP12 72h Significance defined by Supp Table. Features sorted by pvalue. 1 (100%) 1 (100%)
COVID113 Interactome_Stukalov_A549_72h_NSP13 1 Interactome A549 NSP13 72h Significance defined by Supp Table. Features sorted by pvalue. 0 (0%) 1 (100%)
COVID114 Interactome_Stukalov_A549_72h_NSP14 2 Interactome A549 NSP14 72h Significance defined by Supp Table. Features sorted by pvalue. 0 (0%) 1 (50%)
COVID115 Interactome_Stukalov_A549_72h_NSP15 4 Interactome A549 NSP15 72h Significance defined by Supp Table. Features sorted by pvalue. 0 (0%) 3 (75%)
COVID116 Interactome_Stukalov_A549_72h_NSP16 2 Interactome A549 NSP16 72h Significance defined by Supp Table. Features sorted by pvalue. 1 (50%) 2 (100%)
COVID117 Interactome_Stukalov_A549_72h_NSP2 1 Interactome A549 NSP2 72h Significance defined by Supp Table. Features sorted by pvalue. 0 (0%) 1 (100%)
COVID118 Interactome_Stukalov_A549_72h_NSP3_MACROD 2 Interactome A549 NSP3_MACROD 72h Significance defined by Supp Table. Features sorted by pvalue. 0 (0%) 1 (50%)
COVID119 Interactome_Stukalov_A549_72h_NSP4 11 Interactome A549 NSP4 72h Significance defined by Supp Table. Features sorted by pvalue. 9 (82%) 9 (82%)
COVID120 Interactome_Stukalov_A549_72h_NSP6 82 Interactome A549 NSP6 72h Significance defined by Supp Table. Features sorted by pvalue. 44 (54%) 71 (87%)
COVID121 Interactome_Stukalov_A549_72h_NSP7 5 Interactome A549 NSP7 72h Significance defined by Supp Table. Features sorted by pvalue. 4 (80%) 4 (80%)
COVID122 Interactome_Stukalov_A549_72h_NSP8 3 Interactome A549 NSP8 72h Significance defined by Supp Table. Features sorted by pvalue. 2 (67%) 3 (100%)
COVID123 Interactome_Stukalov_A549_72h_NSP9 6 Interactome A549 NSP9 72h Significance defined by Supp Table. Features sorted by pvalue. 4 (67%) 4 (67%)
COVID124 Interactome_Stukalov_A549_72h_ORF3 300 Interactome A549 ORF3 72h Significance defined by Supp Table. Features sorted by pvalue. 197 (66%) 224 (75%)
COVID125 Interactome_Stukalov_A549_72h_ORF7A 55 Interactome A549 ORF7A 72h Significance defined by Supp Table. Features sorted by pvalue. 39 (71%) 31 (56%)
COVID126 Interactome_Stukalov_A549_72h_ORF7B 300 Interactome A549 ORF7B 72h Significance defined by Supp Table. Features sorted by pvalue. 203 (68%) 211 (70%)
COVID127 Interactome_Stukalov_A549_72h_ORF8 29 Interactome A549 ORF8 72h Significance defined by Supp Table. Features sorted by pvalue. 18 (62%) 25 (86%)
COVID128 Interactome_Stukalov_A549_72h_ORF9B 2 Interactome A549 ORF9B 72h Significance defined by Supp Table. Features sorted by pvalue. 1 (50%) 2 (100%)
COVID129 Interactome_Stukalov_A549_72h_S 2 Interactome A549 S 72h Significance defined by Supp Table. Features sorted by pvalue. 1 (50%) 2 (100%)
COVID130 Phosphoproteome_Stukalov_A549-ACE2_24h_Down 300 Phosphoproteome A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 168 (56%) 237 (79%)
COVID131 Phosphoproteome_Stukalov_A549-ACE2_24h_Up 300 Phosphoproteome A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 190 (63%) 244 (81%)
COVID132 Phosphoproteome_Stukalov_A549-ACE2_6h_Down 69 Phosphoproteome A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 51 (74%) 64 (93%)
COVID133 Phosphoproteome_Stukalov_A549-ACE2_6h_Up 69 Phosphoproteome A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 43 (62%) 61 (88%)
COVID134 Proteome_Stukalov_A549-ACE2_24h_Down 299 Proteome A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 177 (59%) 227 (76%)
COVID135 Proteome_Stukalov_A549-ACE2_24h_Up 131 Proteome A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 92 (70%) 105 (80%)
COVID136 Proteome_Stukalov_A549-ACE2_6h_Down 10 Proteome A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 9 (90%) 9 (90%)
COVID137 Proteome_Stukalov_A549-ACE2_6h_Up 8 Proteome A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 8 (100%) 5 (62%)
COVID138 Proteome_Stukalov_A549_72h_E_Down 238 Proteome A549 E Control 72h Significance defined by Supp Table. Features sorted by pvalue. 203 (85%) 154 (65%)
COVID139 Proteome_Stukalov_A549_72h_E_Up 186 Proteome A549 E Control 72h Significance defined by Supp Table. Features sorted by pvalue. 143 (77%) 126 (68%)
COVID140 Proteome_Stukalov_A549_72h_M_Down 168 Proteome A549 M Control 72h Significance defined by Supp Table. Features sorted by pvalue. 142 (85%) 99 (59%)
COVID141 Proteome_Stukalov_A549_72h_M_Up 103 Proteome A549 M Control 72h Significance defined by Supp Table. Features sorted by pvalue. 82 (80%) 80 (78%)
COVID142 Proteome_Stukalov_A549_72h_NSP10_Down 32 Proteome A549 NSP10 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 26 (81%) 19 (59%)
COVID143 Proteome_Stukalov_A549_72h_NSP10_Up 49 Proteome A549 NSP10 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 39 (80%) 37 (76%)
COVID144 Proteome_Stukalov_A549_72h_NSP12_Down 210 Proteome A549 NSP12 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 145 (69%) 129 (61%)
COVID145 Proteome_Stukalov_A549_72h_NSP12_Up 40 Proteome A549 NSP12 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 31 (78%) 18 (45%)
COVID146 Proteome_Stukalov_A549_72h_NSP13_Down 97 Proteome A549 NSP13 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 58 (60%) 77 (79%)
COVID147 Proteome_Stukalov_A549_72h_NSP13_Up 120 Proteome A549 NSP13 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 95 (79%) 79 (66%)
COVID148 Proteome_Stukalov_A549_72h_NSP14_Down 39 Proteome A549 NSP14 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 30 (77%) 28 (72%)
COVID149 Proteome_Stukalov_A549_72h_NSP14_Up 45 Proteome A549 NSP14 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 32 (71%) 35 (78%)
COVID150 Proteome_Stukalov_A549_72h_NSP15_Down 34 Proteome A549 NSP15 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 29 (85%) 21 (62%)
COVID151 Proteome_Stukalov_A549_72h_NSP15_Up 69 Proteome A549 NSP15 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 56 (81%) 48 (70%)
COVID152 Proteome_Stukalov_A549_72h_NSP16_Down 39 Proteome A549 NSP16 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 36 (92%) 26 (67%)
COVID153 Proteome_Stukalov_A549_72h_NSP16_Up 65 Proteome A549 NSP16 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 54 (83%) 41 (63%)
COVID154 Proteome_Stukalov_A549_72h_NSP1_Down 214 Proteome A549 NSP1 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 128 (60%) 127 (59%)
COVID155 Proteome_Stukalov_A549_72h_NSP1_Up 128 Proteome A549 NSP1 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 83 (65%) 80 (62%)
COVID156 Proteome_Stukalov_A549_72h_NSP2_Down 121 Proteome A549 NSP2 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 87 (72%) 80 (66%)
COVID157 Proteome_Stukalov_A549_72h_NSP2_Up 69 Proteome A549 NSP2 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 47 (68%) 44 (64%)
COVID158 Proteome_Stukalov_A549_72h_NSP3_MACROD_Down 48 Proteome A549 NSP3_MACROD Control 72h Significance defined by Supp Table. Features sorted by pvalue. 38 (79%) 35 (73%)
COVID159 Proteome_Stukalov_A549_72h_NSP3_MACROD_Up 79 Proteome A549 NSP3_MACROD Control 72h Significance defined by Supp Table. Features sorted by pvalue. 53 (67%) 57 (72%)
COVID160 Proteome_Stukalov_A549_72h_NSP4_Down 41 Proteome A549 NSP4 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 31 (76%) 28 (68%)
COVID161 Proteome_Stukalov_A549_72h_NSP4_Up 82 Proteome A549 NSP4 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 56 (68%) 52 (63%)
COVID162 Proteome_Stukalov_A549_72h_NSP6_Down 68 Proteome A549 NSP6 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 52 (76%) 41 (60%)
COVID163 Proteome_Stukalov_A549_72h_NSP6_Up 64 Proteome A549 NSP6 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 44 (69%) 39 (61%)
COVID164 Proteome_Stukalov_A549_72h_NSP7_Down 34 Proteome A549 NSP7 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 26 (76%) 22 (65%)
COVID165 Proteome_Stukalov_A549_72h_NSP7_Up 39 Proteome A549 NSP7 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 23 (59%) 26 (67%)
COVID166 Proteome_Stukalov_A549_72h_NSP8_Down 60 Proteome A549 NSP8 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 46 (77%) 43 (72%)
COVID167 Proteome_Stukalov_A549_72h_NSP8_Up 52 Proteome A549 NSP8 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 40 (77%) 32 (62%)
COVID168 Proteome_Stukalov_A549_72h_NSP9_Down 42 Proteome A549 NSP9 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 35 (83%) 26 (62%)
COVID169 Proteome_Stukalov_A549_72h_NSP9_Up 55 Proteome A549 NSP9 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 47 (85%) 36 (65%)
COVID170 Proteome_Stukalov_A549_72h_N_Down 137 Proteome A549 N Control 72h Significance defined by Supp Table. Features sorted by pvalue. 114 (83%) 97 (71%)
COVID171 Proteome_Stukalov_A549_72h_N_Up 103 Proteome A549 N Control 72h Significance defined by Supp Table. Features sorted by pvalue. 83 (81%) 70 (68%)
COVID172 Proteome_Stukalov_A549_72h_ORF3_Down 300 Proteome A549 ORF3 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 209 (70%) 207 (69%)
COVID173 Proteome_Stukalov_A549_72h_ORF3_Up 291 Proteome A549 ORF3 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 203 (70%) 214 (74%)
COVID174 Proteome_Stukalov_A549_72h_ORF6_Down 79 Proteome A549 ORF6 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 64 (81%) 56 (71%)
COVID175 Proteome_Stukalov_A549_72h_ORF6_Up 90 Proteome A549 ORF6 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 62 (69%) 55 (61%)
COVID176 Proteome_Stukalov_A549_72h_ORF7A_Down 67 Proteome A549 ORF7A Control 72h Significance defined by Supp Table. Features sorted by pvalue. 54 (81%) 47 (70%)
COVID177 Proteome_Stukalov_A549_72h_ORF7A_Up 74 Proteome A549 ORF7A Control 72h Significance defined by Supp Table. Features sorted by pvalue. 56 (76%) 47 (64%)
COVID178 Proteome_Stukalov_A549_72h_ORF7B_Down 123 Proteome A549 ORF7B Control 72h Significance defined by Supp Table. Features sorted by pvalue. 95 (77%) 82 (67%)
COVID179 Proteome_Stukalov_A549_72h_ORF7B_Up 130 Proteome A549 ORF7B Control 72h Significance defined by Supp Table. Features sorted by pvalue. 96 (74%) 92 (71%)
COVID180 Proteome_Stukalov_A549_72h_ORF8_Down 62 Proteome A549 ORF8 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 44 (71%) 39 (63%)
COVID181 Proteome_Stukalov_A549_72h_ORF8_Up 79 Proteome A549 ORF8 Control 72h Significance defined by Supp Table. Features sorted by pvalue. 49 (62%) 53 (67%)
COVID182 Proteome_Stukalov_A549_72h_ORF9B_Down 218 Proteome A549 ORF9B Control 72h Significance defined by Supp Table. Features sorted by pvalue. 116 (53%) 134 (61%)
COVID183 Proteome_Stukalov_A549_72h_ORF9B_Up 116 Proteome A549 ORF9B Control 72h Significance defined by Supp Table. Features sorted by pvalue. 68 (59%) 78 (67%)
COVID184 Proteome_Stukalov_A549_72h_S_Down 48 Proteome A549 S Control 72h Significance defined by Supp Table. Features sorted by pvalue. 36 (75%) 29 (60%)
COVID185 Proteome_Stukalov_A549_72h_S_Up 64 Proteome A549 S Control 72h Significance defined by Supp Table. Features sorted by pvalue. 47 (73%) 41 (64%)
COVID186 RNA_Stukalov_A549-ACE2_12h_Down 18 RNA-seq A549-ACE2 SARS-CoV-2 Mock 12h Significance defined by Supp Table. Features sorted by pvalue. 17 (94%) 13 (72%)
COVID187 RNA_Stukalov_A549-ACE2_12h_Up 13 RNA-seq A549-ACE2 SARS-CoV-2 Mock 12h Significance defined by Supp Table. Features sorted by pvalue. 10 (77%) 11 (85%)
COVID188 RNA_Stukalov_A549-ACE2_18h_Down 32 RNA-seq A549-ACE2 SARS-CoV-2 Mock 18h Significance defined by Supp Table. Features sorted by pvalue. 26 (81%) 15 (47%)
COVID189 RNA_Stukalov_A549-ACE2_18h_Up 66 RNA-seq A549-ACE2 SARS-CoV-2 Mock 18h Significance defined by Supp Table. Features sorted by pvalue. 54 (82%) 61 (92%)
COVID190 RNA_Stukalov_A549-ACE2_24h_Down 38 RNA-seq A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 25 (66%) 26 (68%)
COVID191 RNA_Stukalov_A549-ACE2_24h_Up 98 RNA-seq A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 82 (84%) 84 (86%)
COVID192 RNA_Stukalov_A549-ACE2_30h_Down 97 RNA-seq A549-ACE2 SARS-CoV-2 Mock 30h Significance defined by Supp Table. Features sorted by pvalue. 46 (47%) 60 (62%)
COVID193 RNA_Stukalov_A549-ACE2_30h_Up 300 RNA-seq A549-ACE2 SARS-CoV-2 Mock 30h Significance defined by Supp Table. Features sorted by pvalue. 163 (54%) 237 (79%)
COVID194 RNA_Stukalov_A549-ACE2_3h_Down 2 RNA-seq A549-ACE2 SARS-CoV-2 Mock 3h Significance defined by Supp Table. Features sorted by pvalue. 2 (100%) 1 (50%)
COVID195 RNA_Stukalov_A549-ACE2_3h_Up 16 RNA-seq A549-ACE2 SARS-CoV-2 Mock 3h Significance defined by Supp Table. Features sorted by pvalue. 8 (50%) 15 (94%)
COVID196 RNA_Stukalov_A549-ACE2_6h_Down 15 RNA-seq A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 14 (93%) 10 (67%)
COVID197 RNA_Stukalov_A549-ACE2_6h_Up 6 RNA-seq A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 6 (100%) 6 (100%)
COVID198 Ubiquitinome_Stukalov_A549-ACE2_24h_Down 196 Ubiquitinome A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 142 (72%) 147 (75%)
COVID199 Ubiquitinome_Stukalov_A549-ACE2_24h_Up 300 Ubiquitinome A549-ACE2 SARS-CoV-2 Mock 24h Significance defined by Supp Table. Features sorted by pvalue. 197 (66%) 242 (81%)
COVID200 Ubiquitinome_Stukalov_A549-ACE2_6h_Down 250 Ubiquitinome A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 167 (67%) 185 (74%)
COVID201 Ubiquitinome_Stukalov_A549-ACE2_6h_Up 100 Ubiquitinome A549-ACE2 SARS-CoV-2 Mock 6h Significance defined by Supp Table. Features sorted by pvalue. 79 (79%) 76 (76%)


 IsOMICS Transcriptomics,  SampleType in vitro,  CellType pHAE cultures,  VirusStrain SARS-CoV-2, 2019-nCoV/WA1,  Timepoints 48 h,  Perturbations ,  HasCompleteData Yes,  GeneListSource Processed from GEO read counts.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined344       234 (68%)
COVID202 RNA_Vanderheiden_pHAE_48h_Down 189 RNA-seq pHAE SARS-CoV-2 Mock 48h Significance defined by Log2FC >= 1.0 and adjusted p-value < 0.01. Features sorted by pvalue. 0 (0%) 124 (66%)
COVID203 RNA_Vanderheiden_pHAE_48h_Up 155 RNA-seq pHAE SARS-CoV-2 Mock 48h Significance defined by Log2FC >= 1.0 and adjusted p-value < 0.01. Features sorted by pvalue. 0 (0%) 110 (71%)

SARS-CoV2 infection in Huh7 cell line and performed transcriptomics and proteomics analysis in uninfected and 24,48,72 hours post infection to identify the host cellular response against SARS-CoV2.

 IsOMICS RNA-Seq, proteomics,  SampleType in vitro,  CellType Huh-7,  VirusStrain SARS-CoV-2,  Timepoints 24, 48, 72 h,  Perturbations ,  HasCompleteData Yes,  GeneListSource Processed from raw reads.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined629       411 (65%)
COVID001 RNA_Appelberg_Huh-7_24h_Down 6 RNA-seq Huh-7 SARS-CoV-2 uninfected 24h 2 (33%) 4 (67%)
COVID002 RNA_Appelberg_Huh-7_24h_Up 8 RNA-seq Huh-7 SARS-CoV-2 uninfected 24h 2 (25%) 7 (88%)
COVID003 RNA_Appelberg_Huh-7_48h_Down 23 RNA-seq Huh-7 SARS-CoV-2 uninfected 48h 17 (74%) 17 (74%)
COVID004 RNA_Appelberg_Huh-7_48h_Up 95 RNA-seq Huh-7 SARS-CoV-2 uninfected 48h 83 (87%) 40 (42%)
COVID005 RNA_Appelberg_Huh-7_72h_Down 300 RNA-seq Huh-7 SARS-CoV-2 uninfected 72h 16 (5%) 237 (79%)
COVID006 RNA_Appelberg_Huh-7_72h_Up 300 RNA-seq Huh-7 SARS-CoV-2 uninfected 72h 84 (28%) 158 (53%)

Gene expression in CD21low and CD21pos B cells from CVID patients.

 IsOMICS RNA-Seq,  SampleType patient samples,  CellType B cells,  VirusStrain SARS-CoV-2,  Timepoints N/A,  Perturbations ,  HasCompleteData Yes,  GeneListSource GEO read counts.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined780       493 (63%)
COVID021 RNA_Keller_B-cells-CD21pos_infection_Down 23 RNA-seq B cells SARS-CoV-2 (CD21+) uninfected (CD21+) 4 (17%) 17 (74%)
COVID022 RNA_Keller_B-cells-CD21pos_infection_Up 269 RNA-seq B cells SARS-CoV-2 (CD21+) uninfected (CD21+) 86 (32%) 172 (64%)
COVID023 RNA_Keller_B-cells-Infected_CD21pos_Down 278 RNA-seq B cells SARS-CoV-2 (CD21+) SARS-CoV-2 (CD21 low) 80 (29%) 185 (67%)
COVID024 RNA_Keller_B-cells-Infected_CD21pos_Up 300 RNA-seq B cells SARS-CoV-2 (CD21+) SARS-CoV-2 (CD21 low) 10 (3%) 175 (58%)


 IsOMICS scRNA-seq, TCR-seq,  SampleType patient samples,  CellType BALF,  VirusStrain SARS-CoV-2,  Timepoints n/a,  Perturbations ,  HasCompleteData yes,  GeneListSource GEO read counts.

COVID IDList NameSizeTechnologySourceTreatmentReferenceTimePointsComments#Found Multiple Times#Found in Other Studies
 Combined1382       813 (59%)
COVID029 RNA_Liao_BALF-mild_Down 300 RNA-seq BALF SARS-CoV-2 (mild) uninfected 120 (40%) 181 (60%)
COVID030 RNA_Liao_BALF-mild_Up 300 RNA-seq BALF SARS-CoV-2 (mild) uninfected 102 (34%) 133 (44%)
COVID031 RNA_Liao_BALF-severe_Down 300 RNA-seq BALF SARS-CoV-2 (severe) uninfected 231 (77%) 150 (50%)
COVID032 RNA_Liao_BALF-severe_Up 300 RNA-seq BALF SARS-CoV-2 (severe) uninfected 153 (51%) 254 (85%)
COVID033 RNA_Liao_BALF-severe-vs-mild_Down 300 RNA-seq BALF SARS-CoV-2 (severe) SARS-CoV-2 (mild) 140 (47%) 117 (39%)
COVID034 RNA_Liao_BALF-severe-vs-mild_Up 300 RNA-seq BALF SARS-CoV-2 (severe) SARS-CoV-2 (mild) 74 (25%) 230 (77%)